During a physical examination, a patient complains of point tenderness in the right upper quadrant of the abdomen. Which organ is likely injured?

Point tenderness in the right upper quadrant of the abdomen is most commonly associated with the liver, which is anatomically located in that area. The liver is a highly vascular organ, and if it sustains injury from trauma or disease, it can lead to pain and tenderness, particularly in the right upper quadrant where it is situated just beneath the rib cage. Such tenderness is often assessed during a physical examination, as it can indicate potential liver injury or other conditions affecting the liver, such as hepatitis or liver cirrhosis.

In this scenario, an injured liver may elicit symptoms of bleeding or distension if there's substantial damage, contributing to discomfort in that specific area. Other organs listed may cause tenderness in various situations, but the specific location of the point tenderness makes the liver the most likely candidate for injury in this case.